"Truth Revealed: New Scientific Discoveries Regarding Mercury in Medicine and Autism" http://reform.house.gov/WHR/Hearings/EventSingle.aspx?EventID=1311
Opening Statement of Chairman Dan
During these investigations, numerous scientists from around the globe have testified before the Committee, and have presented credible peer-reviewed research studies that indicated a direct link between the exposure of Mercury, a widely known neurotoxin, and the increasing incidences of autism.
....Recently, credible researchers from many of our Nation’s most highly regarded research universities have published studies noting the possible associations between Mercury and health defects.
Dr. Richard Deth, Professor at the College of Pharmaceutical Studies at Northeastern University, was the lead researcher in a collaboration between Johns Hopkins University, Tufts University, the University of Nebraska, and Northeastern University on a groundbreaking study into the possible correlation between increases in environmental toxins such as thimerosal and incidences of autism. Dr. Deth will testify on the findings and future implications of his research.
....Another innovative study was conducted at Columbia University recently. Released in June of this year, the researchers exposed mice to Thimerosal in doses and timing, which corresponds to the current pediatric immunization schedule.
....The independent Columbia University study indicates that subjects with a specific genetic susceptibility toward autism are placed at a greater risk for neurodevelopmental diseases when administered Thimerosal-containing vaccines. Unfortunately, Dr. Mady Hornig, the lead researcher on this project, is unable to be with us this morning due to a personal emergency. In her place, Dr. Deth will present her oral testimony.
....As many of us already know, the incidences of autism have become increasingly prevalent in modern-day society. Once considered a rare disease, effecting roughly 1 in 10,000 children, autism now affects 1.5 Million of our Nation’s children, and this problem continues to escalate rapidly.
....According to a recent “Autism Alarm” released by the U.S. Department of Health and Human Services (HHS), the Centers for Disease Control (CDC), and the American Academy of Pediatrics, currently 1 out of every 6 children are diagnosed with a developmental disorder and / or behavioral problem.
....Even more alarming, today 1 out of every 166 children in the United States is being diagnosed with an Autism Spectrum Disorder. This major healthcare crisis is clearly reaching epidemic proportions, and will not just simply “go away.”
Testimony of Melinda Wharton, MD, MPH; Acting Deputy Director; National Immunization Program; CDC; HHS
Testimony of William Egan, PhD; Acting Director; Office of Vaccines Research and Review; Center for Biologics Evaluation and Research; FDA; HHS
Testimony of Mady Hornig, PhD; Asst. Professor of Epidemiology; Columbia University
Testimony of Richard Deth, PhD; Bouve College of Health and Sciences; Dept. of Pharmaceutical Services; Northeastern University
Autism is a neurological disorder caused by dysfunctional metabolic control over methylation reactions, and thimerosal appears to be a precipitating causative factor in many cases. The methionione cycle and the trans-sulfuration pathway leading to cysteine and glutathione synthesis are abnormal in autism. Genetic polymorphisms, present in only a small subpopulation, represent risk factors for autism. As illustrated in Fig. 11, some of these genetic factors impair detoxification and clearance of heavy metals, including thimerosal, and also impair the capacity for methylation. Delayed clearance of thimerosal further impairs methylation, including both DNA methylation and dopamine-stimulated phospholipid methylation, adversely affecting growth factor-directed development and the capacity for attention, respectively. Autism can be treated, and some of the most effective treatments, such as methylcobalamin, act by improving methylation. This encouraging therapeutic development reinforces the conclusion that thimerosal does indeed cause autism, and it does this by interfering with methylcobalamin synthesis. This molecular understanding should lead to new and improved treatments for autism and should provide a scientifically sound basis for the removal of thimerosal from all vaccines.
Testimony of Marcel Just, PhD; D.O. Hebb Professor of Psychology; Director for the Center for Cognitive Brain Imaging; Carnegie Mellon University
Testimony of Richard Fischer, DDS; Int'l Academy of Oral Medicine and Toxicology
Testimony of Lyn Redwood, RN, MSN; President; Safeminds