In clinical trials averaging 6 weeks, Zyprexa was tested in 2,500 adults. The drug was linked to serious, in some cases life-threatening side effects requiring hospitalization in 22% of those tested.... During those 6 week clinical trials there were 20 deaths, of which 12 were suicides. [Nov 2004] Eli Lilly’s highly touted new anti-psychotic, ZyprexaIn fact, I think the newer drugs will eventually be seen as more dangerous than the old drugs, if that's possible. As you know, the standard neuroleptics like Thorazine and Haldol have had quite a litany of harm with the tardive dyskinesia and all.
A couple things to know about the new
drugs, the atypicals. First of all, the clinical trials to test them were
totally bogus. They were designed to make the old drugs look bad and the new
drugs look good. That's coming out now, the fact that these studies painted an
exaggerated picture of the atypicals. They may be no more efficacious and they
may have just as many side-effects as the older neuroleptics. So that tells you
there's plenty of reason to worry. Now that we've had them out for eight to ten
years, we're finding out all sorts of problems.
The good story is that in some instances they're using lower dosages of these atypicals, and because they're using lower dosages, people are finding them less problematic. They don't clamp down as strongly on the dopamine system as the old drugs. So that's good and hopeful.
The negative part is this: They've clearly lied about what these drugs do. They're powerful drugs and they work on a number of neurotransmitter systems. And they clearly are problematic. With olanzapine [marketed as Zyprexa], you're going to see that. Just as tardive dyskinesia was lying in wait all the time with the standard neuroleptics, diabetes is there with olanzapine, big time. And diabetes is a life-threatening, life-shortening disease. So you give that drug to a 12-year-old, a 15-year-old, an 18-year-old and they develop diabetes and 80 pounds of weight gain -- that is a very harmful thing. [Interview 2005] Psychiatry's Untold History of Cruelty, Torture, Eugenics and Brain Damage