One Answer To Cancer by Dr. William Donald Kelley, D.D.S., M.S.  


Pancreatic Enzymes

Reprinted by permission of Author

Jim Dews, Pharmacologist

Dews Research Laboratories

There have been many questions about pancreatic enzymes or peptones. We would like to answer these questions for you and provide valuable information concerning pancreatic enzymes.

First, we would like to explain what a peptone is. A peptone is a secondary Protein, usually from an animal source, that has been changed into a water soluble form. Peptones are excellent carriers for enzymes. As a means of understanding what we mean by the word "carrier", think of the word "bucket" instead. Think of the word "water" as being similar to the "enzymes". The bucket serves as the carrier for the water. Peptones are the carriers for enzymes.

Second, we would like to explain what enzymes are. Enzymes are complex proteins that help break down proteins, carbohydrates and fats in the diet and make them in usable forms. Enzymes help change the nutrients a person consumes in the diet into forms that the body can utilize. They regulate the release of energy from foods or nutrients so the body can use it most efficiently.

Next, we would like to explain the relationship of enzyme activity of pancreas peptones. Pancreatic enzymes have three primary enzymatic activities:

1) PROTEASES - which have the ability to digest proteins.

2) AMYLASES - which have the ability to digest carbohydrates.

3) LIPASES - which have the ability to digest fats.

To determine the source of a peptone (is it derived from pork or beef?), you can look at the proteases, amylases, and lipases NF units. Cows have relatively no fat in their diet. They do not eat meat, therefore they do not need a very high fat digestion ability in their pancreas. Hogs have high percentages of fat in their diet. They are meat eaters, therefore they need a higher fat digesting ability in their pancreas. And thus, pancreatin derived from a porcine (pork) source always has a much higher lipase digesting ability (NF units).

Under each of the primary enzymatic activities, there are secondary enzymatic activities. The secondary enzymes are:

1) TRYPSIN - which has the ability to digest certain types of protein. It has the ability to digest dead tissue or nutrients that have been isolated from their original source.

2) CHYMOTRYPSIN - which has the ability to digest many other types of proteins. It has the ability to digest live tissue or nutrients that have not been isolated.

Many pancreas products have been introduced in recent years by other companies in an attempt to copy our products. They are not the same. Consumers should be aware of cheap imitations or substitutes that could possibly be useless formulas with useless abilities.

When shopping for a pancreatic enzyme product, there are many factors to be considered in your decision making. The most important of these include:





There are certain factors that can destroy the enzymatic activity of the pancreatic enzymes. They are heat, incorrect processing, inadequate forms or extreme acidic or alkaline conditions.

Some companies use extreme heat in processing the pancreatic enzymes. Heat destroys all of the enzymes and makes the product useless. Other companies may use the hydrocarbon solvents or salts in processing their products. Hydrocarbon solvents such as acetone are used to cut corners and may leave substantial residues in the pancreatic enzymes. This process is called "Azeotrophic". Salts are bad because it breaks down the enzymatic activity and medical evidence has shown that high levels of salt can increase blood pressure.


Pancreatic enzymes must be in the correct form in order to reach the lower tract, where it must be in order to perform its functions properly.

To fully understand the process of pancreatic enzymes in the human body, see the following illustration. Digestion starts in the mouth. The pancreatic supplement travels down the esophagus, through the stomach, where it must be in an enteric matrix so stomach acids will not inactivate the enzymatic activity of the pancreatic enzymes. It then travels to the small intestine (duodenum). In the duodenum the pancreatin actually starts its functions. It is important that a pancreatic enzyme includes ox bile, so that when the supplement travels on into the large intestine (colon) it can further perform its functions. Ox bile helps break down the fats in the large intestine. The pancreatic enzymes finally complete their journey through the colon.

If the product is in a capsule form it will not work because the stomach acids will inactivate the pancreatic enzymes, thus making the product useless. The only known capsule form that will work is a microencapsulated matrix beadlet form. This process is time consuming and the most expensive method. Enteric coating is the old fashioned method. If the enteric coating has any indications of cracks or if a crack is caused when it reaches the stomach, then the stomach acids could get into the tablet and inactivate the enzymes rendering the product useless.

The best and correct form is an enteric matrix. An enteric matrix is mixed throughout the entire caplet or tablet. It ensures that the pancreatic enzymes will go to the lower tract where they are protected from stomach acids and where they will go into the bloodstream.



It is also important to understand what a label is claiming. Some labels indicate that the product has been standardized and no sugars are used. This is not true. If the label indicates that the product has been standardized to a particular potency such as 2X, 4X or any other NF units, then federal law requires that it be cut with lactose, which is known as milk sugar.

Some labels also claim their products are derived from beef. In order for the product to be derived from beef, the lipase (NF units) will be lower than the protease and amylase (NF units).



Naturally, in processing our own products at the College Health Store, we utilize methods and raw elements which we consider to be the finest possible.

Look for all-natural ingredients with no hydrocarbon solvents, sugars, salts or fillers. Pancreatin should be derived from beef (ours comes from range-fed, American beef) and in the enteric matrix most suitable for entering the lower digestive tract.

 For more information on this product, contact the College Health store at:



Phone (316) 290-2129

Open 9am - 5pm Central Time