(Ped Infect Dis J 1995
jul;14(7): 588-94)again why? We all know that NSAIDS
like tylenol and iboprofen are implicated.
Another one (Infect Med 16 (5):307, 1999 noted severe
Group A beta-hemolytic strap in children who had had
MMWR, May 15, 1998, Vol 47 No 18 listed chickenpox
cases too.But these parents don't appear to have been
asked about Nonsteroid anti-inflammatories, or -
Pediatrics Vol 103, No 4, April 1999, pg 783+ again
noted the association of ibuprofen with serious
complications - and elsewhere in the same issue.
Acta Paediatri Jpn 1994 Aug;36(4):375-8 shows that
administration of any antipyretic drugs in children
with infectious diseases worsens their illnesses.
Why? Because it appears that anti-pyretics down-
regulate the immune response. This is only natural,
since the reason for a fever is to switch on certain
cytokines, and push the immune system up from the
fourth gear to the tenth (prely as an imagery picture,
here), to help deal with the problem. There is very
clear evidence that tylenol creates an ineffective
immune system in some children, and as Ped Infect Dis
1996:15: 355-53 points out about the immune system in
general - not in particular to Tylenot - "an
ineffective immune response to certain organisms can
result in life-threatening infection."
Better yet, a Journal called Family Practice, Volume
13, No 2, 1996 stated:
"Paracetamol prescribing is reaching epidemic
proportions and the potential dangers of hepatotoxicity
and the inhibition of the immune response in children
He goes on to say:
"Despite our lack of knowledge about its therapeutic
mechanism, it has been claimed to be a safe frug,
especially for children...there is mounting evidence
that paracetamil is not the benign drug that it was
formally thought to be... We would question the whole
rational of prescribing the drug in near epidemic
proportions...there is little concern about its use in
the short term as an ANALGESIC, there is considerable
controversy over its use as an
antipyretic...paracetamol may decrease antibody
response to infection and increase morbidity and
mortality in severe infections....too many parents and
health workers think that fever is bad and needs to be
suppressed by paracetamio, when indeed, moderate fever
may improve the immune response."
In another earlier study in the Lancet March 9, 1991 pg
591 it was stated "Studies have clearly shown that
fever helps laboratory animals to survive an infection
whereas antipyresis increases mortality (death).
Moreover, there is considerable in-vitro evidence that
a variety of human immunological defences function
better at febrile temperatures than at normal ones."
It is a natural thing to say that if your child was
vaccinated against chickenpox, they won't get it (....?
maybe) so you then wouldn't have to worry about the use
tylenol should never be used in any
case of infectious disease, for several reasons -
first, it suppresses the immune system. Second it
makes most children sleepy. Third - the combination of
those two factors can mask critical symptoms which
would alert a parent to a problem, so that as in the
case of many if not most of the recent chickenpox
cases - by the time they get to hospital, the situation
is very severe indeed.
Do you think then, in the light of the literature, all
parents should be warned that while they can use
Tylenol, or paracetamol as as ANALGESIC - or pain
relief, that they should never use it for infectious