Gardasil  Infertility

Gardasil Destroys Girl’s Ovaries: It Should Have Been Predicted

October 18, 2012

A huge array of terrible effects have been attributed to Gardasil. They were predictable—and we’re likely to see many more over the next few years. Here’s why it could, and should, have been predicted.

by Heidi Stevenson

As noted in Gardasil Destroys Girl’s Ovaries: Research on Ovaries Never Considered, the BMJ has published the case report of a healthy 16-year-old Australian girl whose womanhood appears to have been stolen by Gardasil vaccinations. She became fully menopausal, her ovaries irrevocably shut down, without experiencing womanhood. That article focuses on the fact that Merck, Gardasil’s developer, had to be aware of potential harm to ovaries and either hid research documenting it or simply didn’t do it.

This article focuses on the how readily so many Gardasil disorders could—and should—have been predicted, simply by examining the known effects of two ingredients.

The article, Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination1, draws direct attention to three primary facts:

These three facts are chilling, but further examination has shown that there’s even worse. Adverse effects like premature menopause—and worse—could, and should, have been predicted.

Two Risky Ingredients

Gardasil contains two ingredients that are known to cause some of the damage that is now being seen. They are polysorbate 80 (brand names Tween 80, Alkest, and Canarcel) and L-histidine. Polysorbate 80 has been shown in at least one study to do great harm to female reproductive organs. The risk from L-histidineis more subtle, as its absence is the issue, but it’s likely more pervasive. The mechanism that would cause a lack of L-histidine is explained.

Polysorbate 80

Polysorbate 80 is known to cause damage to female rats’ reproductive system2, and there is no reason to believe that the human reproductive system is spared. Delayed effects of neonatal exposure to Tween 80 on female reproductive organs in rats states:

Treatment with Tween 80 accelerated maturation, prolonged the oestrus cycle, and induced persistent vaginal oestrus. The relative weight of the uterus and ovaries was decreased relative to the untreated controls. Squamous cell metaplasia of the epithelial lining of the uterus and cytological changes in the uterus were indicative of chronic oestrogenic stimulation. Ovaries were without corpora lutea, and had degenerative follicles.

Surely it should come as no surprise that at least one girl’s ovaries were lost after taking Gardasil vaccinations. It was predictable.

Polysorbate 80 can cause anaphylactic shock. A study in the Annals of Allergy, Asthma & Immunology3 concluded:

Polysorbate 80 is a ubiquitously used solubilizing agent that can cause severe nonimmunologic anaphylactoid reactions.

The most frightening trait of polysorbate 80 may be that it crosses the blood-brain barrier and can take other substances with it. It is used for that purpose. The drugs loperamide4 and doxorubicin5 are coated with polysorbate for just this purpose—to drag them into the brain.

So what else can polysorbate 80 drag into the brain? Gardasil utilizes aluminum as an adjuvant, even though it’s a dangerous neurotoxin. Injection of aluminum is associated with several neurological disorders, as is reported in Gaia Health and Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations6, rheumatoid arthritis, autoimmune thyroid disease, inflammatory bowel disease, multiple sclerosis, diabetes, and autism may all be associated with aluminum adjuvants in vaccines.

Can polysorbate open the blood-brain barrier to let aluminum in? No one really knows because no one has looked. There is, though, no legitimate reason to assume that it cannot.

Considering how significant the risks of polysorbate 80 are, surely the precautionary rule should be applied before mass vaccinations of girls. And then there’s L-Histidine …


L-histidine is a precursor of histamine, which triggers the inflammation response in allergic reactions. We may think of histamine as negative, but it is, in fact, crucial for health. Though it can be excessive in the inflammatory response it triggers in allergic reactions, we wouldn’t survive without the inflammation it triggers in general infections.

L-histidine is an essential amino acid with several other functions, including7:

Low levels of L-histidine have been associated with rheumatoid arthritis7. It’s required for processing and chelation of copper, zinc, cobalt, and iron8,9,10,11, all of which are classed as heavy metals and noted for causing a variety of severe disorders when held in the body in excessive amounts.

Excessive amounts of these heavy metals can result in a large array of symptoms and conditions, including the milder ones of:

All of these symptoms are frequently reported by girls who are given the Gardasil vaccine. The question is: How do these symptoms of heavy metal intoxication relate to L-histidine in Gardasil? L-histidine is a necessary amino acid. It’s normally found in the body. All of these symptoms are related to inadequate amounts of the substance, so how can injecting it result in less L-histidine?

It is the seemingly innocuous nature that’s at issue. L-histidine is an amino acid that naturally occurs in the body. So too does squalene occur in the body naturally. It’s one of a group of oils used as adjuvants. However, they are not used in vaccines for human beings, with the insane and devastating exception of squalene. They are used to induce autoimmune disorders in laboratory animals so that they can be studied for response to potential treatments for those disorders. That’s why squalene is so dangerous and is clearly what’s behind Gulf War Syndrome. You can read about the likely connection between squalene and  Swedish and Finnish narcolepsy outbreaks in How the Flu Vaccine Causes Narcolepsy.

Unless otherwise demonstrated, it must be assumed that injecting L-histidine can result in an autoimmune disorder in which L-histidine is attacked by the immune system, resulting in a shortage of it and the substances requiring it for manufacture.

For example:

It was entirely predictable that any bodily function that relies on L-histidine or one of the substances for which it’s a precursor, including histamine, carnosine, and anserine, could be affected. It should come as no surprise that adverse effects of Gardasil include a wide range of disorders and deaths. It would have been surprising had Gardasil not produced them!


Gardasil may be the first vaccine to utilize L-histidine. The reason it’s included doesn’t seem to be explained anywhere. The adverse effects of polysorbate 80 are well known, especially when it’s injected. Polysorbate 80′s ability to bypass the blood-brain barrier is not new information; yet, it was included in this vaccine that utilizes a known neurotoxin, aluminum.

The question that must be asked is: Why? What reason could possibly exist for a vaccine that could predictably result in such incredible harm? Much of the potential damage will likely not be seen for years. Will be find that the already-high rate of infertility skyrockets? Will those who do manage to conceive suffer the anguish of miscarriages and babies with birth defects? How many will suffer from autoimmune disorders, such as rheumatoid arthritis? How many will suffer from neurological disorders, such as the Tourette’s-like tics suffered by girls in New York?

Joel Lord refers to Gardasil, along with Cervarix, as A Legacy of Shame. We are now seeing only the beginning of the adverse effects that have likely been caused. Autoimmune disorders tend to take time to show up. It takes time before pubescent girls become sexually active. How many of them will never experience the potential of sexual intimacy because the vaccine’s L-histidine has stolen their ability of sexual arousal and orgasm?

The simplest reason of all is, of course, money. Merck and its minions simply value money over anything else, including the quality of countless young women’s lives. Nor do they appear to care how many will suffer early deaths. Are there other reasons? In my view, nothing could be more insidious than to willingly hide the terrible and predictable potential of a product simply to get rich. Others, though, see this as part of a conspiracy. What are your views?

Cynthia A. Janak investigated Gardasil ingredients polysorbate 80 and L-histidine with horror. Although I don’t share her suspicion that the problem is caused by a synergistic relationship between the two, her work has been indispensable. You can read about her findings in Polysorbate 80 and Histidine, a marriage of disaster. I have discussed this issue with Leslie Carol Botha of Holy Hormones!, who referred me to Cynthia Janak’s work. This article would not have been produced without the insights of both these women. 


  1. Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccinationBMJ Reports 2012, Deirdre Therese Little, Harvey Rodrick Grenville Ward, doi:10.1136/bcr-2012-006879
  2. Delayed effects of neonatal exposure to Tween 80 on female reproductive organs in rats.
  3. Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions.
  4. Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles.
  5. Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles.
  6. Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
  7. Pure L-Histidine
  8. Synthesis and characterization of copper(I), copper(II), zinc(II), cobalt(II), and iron(II) complexes of a chelating ligand derived from 2,6-diacetylpyridine and L-histidine. Oxygenation of the copper(I), cobalt(II), and iron(II) complexes. Crystal structure of the zinc(II) complex
  9. Dietary regulation of copper absorption and storage in rats: effects of sodium, zinc and histidine-zinc.
  10. Growth characteristics in laboratory animals fed zinc-deficient, copper-deficient, of histidine-supplemented diets.
  11. Inhibition of copper absorption by zinc. Effect of histidine.
  12. Low free serum histidine concentration in rheumatoid arthritis. A measure of disease activity.
  13. Histidine Suppresses Food Intake through Its Conversion into Neuronal Histamine
  14. Histamine: A potential therapeutic agent for breast cancer treatment?