Bullous pemphigoid & vaccine citations
Medical citations  Skin disorders

Bullous pemphigoid is a blistering disease that usually occurs in people over fifty years of age. The blisters are large and can occur anywhere on the skin but are more common on the skin fold areas such as the groin and armpits. Bullous pemphigoid can also involve the mouth. The disease is rarely life-threatening. 

Downs AM, et al.     Does influenza vaccination induce bullous pemphigoid? A report of four cases. Br J Dermatol. 1998 Feb;138(2):363. No abstract available.PMID: 9602897; UI: 98265607.

Baykal C, Okan G, Sarica R. Childhood bullous pemphigoid developed after the first vaccination  .J Am Acad Dermatol. 2001 Feb;44(2 Suppl):348-50. PMID: 11174412 [PubMed - indexed for MEDLINE]

Bodokh I, et al.    [Reactivation of bullous pemphigoid after influenza vaccination]. Therapie. 1994 Mar-Apr;49(2):154. French. No abstract available.PMID: 7817351; UI: 95117082.
Erbagci Z.  Childhood bullous pemphigoid following hepatitis B immunization. J Dermatol. 2002 Dec;29(12):781-5.PMID: 12532044 [PubMed - in process]
Bullous pemphigoid (BP) is an acquired autoimmune bullous disorder which predominantly affects the elderly. It is very rare in children. There are approximately 50 reported cases of childhood BP. Although the cause of childhood BP is unknown, drug intake and vaccination have been incriminated in some cases. A total of 13 patients with BP (10 adults and 3 infants) have been described to be related to various vaccines and tetanus toxoid booster. However, no case related to hepatitis B vaccination has previously been reported. Our case of childhood BP developed one week after hepatitis B immunization in a Turkish caucasian child. This case suggests that the hepatitis B surface antigen can function as the triggering factor for BP by inducing a nonspecific immune reactivation which unmasks subclinical BP or by stimulating a specific antibody production that may cross-react with BP antigens.  PMID: 12532044
Fournier B, et al.    Bullous pemphigoid induced by vaccination. Br J Dermatol. 1996 Jul;135(1):153-4. No abstract available.PMID: 8776390; UI: 96372575.    
Lear JT, et al. Bullous pemphigoid following influenza vaccination. Clin Exp Dermatol. 1996 Sep;21(5):392. No abstract available.PMID: 9136169; UI: 97281896.
Schmutz JL, et al.   [Does influenza vaccination induce bullous pemphigoid]? Ann Dermatol Venereol. 1999 Oct;126(10):765. French. No abstract available.PMID: 10604026; UI: 20071693.  

[Home]  [Vaccination]   [Diseases]  [Vaccine damage]