Bullous pemphigoid & vaccine citations
Medical citations Skin disorders
Bullous pemphigoid is a blistering disease that usually occurs in people
over fifty years of age. The blisters are large and can occur anywhere on the skin but are
more common on the skin fold areas such as the groin and armpits. Bullous pemphigoid can
also involve the mouth. The disease is rarely life-threatening.
AM, et al. Does influenza vaccination induce bullous
pemphigoid? A report of four cases. Br J Dermatol. 1998 Feb;138(2):363. No abstract
available.PMID: 9602897; UI: 98265607.
C, Okan G, Sarica R. Childhood bullous pemphigoid developed after the
first vaccination .J Am Acad Dermatol. 2001 Feb;44(2 Suppl):348-50.
PMID: 11174412 [PubMed - indexed for MEDLINE]
I, et al. [Reactivation of bullous pemphigoid after influenza
vaccination]. Therapie. 1994 Mar-Apr;49(2):154. French. No abstract available.PMID:
7817351; UI: 95117082.
Childhood bullous pemphigoid following hepatitis B immunization.
J Dermatol. 2002 Dec;29(12):781-5.PMID: 12532044
[PubMed - in process]
Bullous pemphigoid (BP) is an acquired autoimmune
bullous disorder which predominantly affects the elderly. It is very rare in
children. There are approximately 50 reported cases of childhood BP. Although
the cause of childhood BP is unknown, drug intake and vaccination have been
incriminated in some cases. A total of 13 patients with BP (10 adults and 3
infants) have been described to be related to various vaccines and tetanus
toxoid booster. However, no case related to hepatitis B vaccination has
previously been reported. Our case of childhood BP developed one week after
hepatitis B immunization in a Turkish caucasian child. This case suggests that
the hepatitis B surface antigen can function as the triggering factor for BP
by inducing a nonspecific immune reactivation which unmasks subclinical BP or
by stimulating a specific antibody production that may cross-react with BP
antigens. PMID: 12532044
B, et al. Bullous pemphigoid induced by vaccination. Br J Dermatol.
1996 Jul;135(1):153-4. No abstract available.PMID: 8776390; UI:
JT, et al. Bullous pemphigoid following influenza vaccination. Clin Exp Dermatol. 1996
Sep;21(5):392. No abstract available.PMID: 9136169; UI: 97281896.
JL, et al. [Does influenza vaccination induce bullous pemphigoid]? Ann Dermatol Venereol. 1999 Oct;126(10):765. French. No abstract available.PMID: 10604026; UI:
[Diseases] [Vaccine damage]