Inflammatory bowel disease (IBD)
(Crohns disease and ulcerative colitis)
MMR/MR Bowel disease [back] Vaccine disease
Dr. Andy Wakefield
Measles-containing vaccines and IBD.-----Andrew Wakefield, 02 January 2002
"I belive that the published data in peer reviewed journals show two things. First, a highly selected group of children with developmental disorder (many with regressive autism) exists, who have an unusual gastrointestinal abnormality characterised by ileal-lymphoid-nodular hyperplasia and non-specific enterocolitis that is not classical inflammatory bowel disease. The immunopathology of this disorder has been studied by Furlano and colleagues, who have established clear differences from chronic inflammatory bowel disease. Second, in such highly selected children, Uhlmann and colleagues(5) have now provided new evidence that measles might be involved."---John Walker-Smith
Another consideration is the ability of attenuated viruses to undergo mutation over time, eventually resulting in organisms that can cause new diseases. When I i ve viruses are used to make vaccines, a process of repeated passage of the virus though growth media reduces its virulence, or the ability of the virus to cause disease. However, as occurs with measles, rubella and many other viruses used in vaccines, once in the body the attenuated viruses can be converted to quite virulent viruses. This is thought to explain the high incidence of Crohn's disease in people who were vaccinated as children with live measles viruses. (Broide, LA., et al. Dig Liver Dis 2001;33(6):472-6.) Vaccine Safety Manual by Neil Z. Miller. (Preface)
As this book demonstrates, the number of immune related disorders, such as lupus, rheumatoid arthritis and asthma, is growing substantially. All of these disorders have been linked by careful studies to vaccines. Vaccine Safety Manual by Neil Z. Miller. (Preface)
Measles theory in Crohn's
Dawbarns solicitors vaccine fact sheet
[BMJ Feb 2002] Letter to the editor...John Walker-Smith
Media vaccine victim stories
[Media 1998 MMR--Chrohn's disease] Vaccine victims' parents set to sue (Rebecca Symington)
Vaccine row parents made to pay for son's diagnosis
Children with adverse effects from Hep B
Tim DITTMAN [Hepatitis B vaccine--Crohn's disease & arthritis]
Thompson, N.P., Montgomery, S.M.., Pounder, R.E., Wakefield, A.J., (29/4/96), Is Measles Vaccination a risk factor for inflammatory bowel disease?, The Lancet, Vol 345: 1071-1073.
Summary: Measles virus may persist in intestinal tissue, particularly that affected by Crohns disease, and early exposure to measles may be a risk factor for the development of Crohns disease. Crohns disease and ulcerative colitis occur in the same families and may share a common aetiology. In view of the rising incidence of inflammatory bowel disease (Crohns disease and ulcerative colitis), we examined the impact of measles vaccination upon these conditions. Prevalence of Crohns disease, ulcerative colitis, coeliac disease, and peptic ulceration were determined in 3545 people who had received live measles vaccine in 1964 as part of a measles vaccine trial. A longitudinal birth cohort of 11,407 subjects was on unvaccinated comparison cohort and 2541 partners of those vaccinated was another. Compared with the birth cohort, the relative risk of developing Crohns disease in the vaccinated group was 3.01 (95% CI 1.45-6.23) and of developing ulcerative colitis was 2.53 (1.15-5.58). There was not significant difference between these two groups in coeliac disease prevalence. Increased prevalence of inflammatory bowel disease, but not coeliac disease or peptic ulcerations, was found in the vaccinated cohort compared with their partners. These findings suggest that measles virus may play a part in the development not only of Crohns diseases by also of ulcerative colitis.
Infant Antibiotic (erythromycin) Can Cause Severe Stomach Disorder (pyloric stenosis )
Baxter T, Radford J.Measles vaccination as a risk factor for inflammatory bowel disease.Lancet. 1995 May 27;345(8961):1363-4. No abstract available.PMID: 7752767 [PubMed - indexed for MEDLINE]
Calman KC. Measles vaccination as a risk factor for inflammatory bowel disease.Lancet. 1995 May 27;345(8961):1362. No abstract available.PMID: 7752763 [PubMed - indexed for MEDLINE]
Davis RL, Kramarz P, Bohlke K, Benson P, Thompson RS, Mullooly J, Black S, Shinefield H, Lewis E, Ward J, Marcy SM, Eriksen E, Destefano F, Chen R. Measles-mumps-rubella and other measles-containing vaccines do not increase the risk for inflammatory bowel disease: a case-control study from the Vaccine Safety Datalink project.Arch Pediatr Adolesc Med. 2001 Mar;155(3):354-9.PMID: 11231801 [PubMed - indexed for MEDLINE]
Farrington P, Miller E. Measles vaccination as a risk factor for inflammatory bowel disease.Lancet. 1995 May 27;345(8961):1362. No abstract available.PMID: 7752764 [PubMed - indexed for MEDLINE]
Lavy A, Broide E, Reif S, Keter D, Niv Y, Odes S, Eliakim R, Halak A, Ron Y, Patz J, Fich A, Villa Y, Arber N, Gilat T. Measles is more prevalent in Crohn's disease patients. A multicentre Israeli study.Dig Liver Dis. 2001 Aug-Sep;33(6):472-6.PMID: 11572573 [PubMed - indexed for MEDLINE]
Morris DL, Montgomery SM, Thompson NP, Ebrahim S, Pounder RE, Wakefield AJ. Measles vaccination and inflammatory bowel disease: a national British Cohort Study.Am J Gastroenterol. 2000 Dec;95(12):3507-12.
Mikula C. Measles vaccination a risk factor for inflammatory bowel disease?Gastroenterol Nurs. 2000 Jul-Aug;23(4):168-71. Review.PMID: 11310084 [PubMed - indexed for MEDLINE]
MacDonald TT. Measles vaccination as a risk factor for inflammatory bowel disease.Lancet. 1995 May 27;345(8961):1363; discussion 1364. No abstract available.PMID: 7752766 [PubMed - indexed for MEDLINE]
Stokkers PC, van den Berg M, Rings E. Measles vaccination and inflammatory bowel disease.J Pediatr Gastroenterol Nutr. 1998 Aug;27(2):239-40. No abstract available.PMID: 9702664 [PubMed - indexed for MEDLINE]
Thompson NP, Pounder RE, Wakefield AJ. Perinatal and childhood risk factors for inflammatory bowel disease: a case-control study.Eur J Gastroenterol Hepatol. 1995 May;7(5):385-90.PMID: 7614098 [PubMed - indexed for MEDLINE]
Thompson NP, Montgomery SM, Pounder RE, Wakefield AJ. Is measles vaccination a risk factor for inflammatory bowel disease?Lancet. 1995 Apr 29;345(8957):1071-4.