BCG (Bacille Calmette-Guerin) vaccine adverse reactions
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"133 Children Contract Tuberculosis in Southern Kazakhstan" http://www.ias.org.nz/kazak.htm
 J. A. Ratón, M.D. Disseminated Bacillus Calmette-Guerin Infection in an HIV-Infected Child: A Case with Cutaneous Lesions This is the first reported case of disseminated BCG infection in an HIV-infected child presenting with cutaneous lesions.
 Hesseling AC et al. BCG-INDUCED DISEASE IN HIV-INFECTED CHILDREN.
BCG cancer therapy:
Arrese M, Ebel L, Hofmann E, Gaete P, Jara A, Cabrera K, Araos F, Del Rio P, Valdivieso V. [Miliary tuberculosis as a complication of BCG immunotherapy in cancer of the bladder. Case report] Rev Med Chil. 1992 Aug;120(8):910-3. Spanish. PMID: 1340967 [PubMed - indexed for MEDLINE]
Peyriere H, Klouche K, Beraud JJ, Blayac JP, Hillaire-Buys D. Fatal systemic reaction after multiple doses of intravesical bacillus Calmette-Guerin for polyposis.Ann Pharmacother. 2000 Nov;34(11):1279-82.PMID: 11098343 [PubMed - indexed for MEDLINE]
Clavel G, Grados F, Cayrolle G, Bellony R, Leduc I, Lafont B, Ducroix JP, Fardellone P. Polyarthritis following intravesical BCG immunotherapy. Report of a case and review of 26 cases in the literature. Rev Rhum Engl Ed. 1999 Feb;66(2):115-8. Review. PMID: 10084173 [PubMed - indexed for MEDLINE]
Donaldson RC, Canaan SA Jr, McLean RB, Ackerman LV. Uveitis and vitiligo associated with BCG treatment for malignant melanoma. Surgery. 1974 Nov;76(5):771-8. No abstract available. PMID: 4424743 [PubMed - indexed for MEDLINE]
A, Marty L, Suc JM, Kleinknecht D, de Fremont JF, Marsepoil T, Veyssier P.Renal
complications of intravesical bacillus Calmette-Guerin therapy.Am J
Nephrol. 1991;11(6):501-4. Review.PMID: 1819218 [PubMed - indexed for MEDLINE]
Price GE. Arthritis and iritis after BCG therapy for bladder cancer. J Rheumatol. 1994 Mar;21(3):564-5. PMID: 8006904
Strausser JL, et al. Pott's disease following BCG therapy of melanoma. Cancer. 1981 Sep 1;48(5):1154-6. PMID: 7272949; UI: 82001867.
The first reported case of a patient with BCG-induced Pott's disease following immunotherapy for melanoma is presented. No signs or symptoms of the disease were detected for 2 1/2 years after therapy. The diagnosis and treatment of this complication of melanoma therapy are discussed. [See Related Articles]
Schult C. [Side effects of BCG immune therapy in 511 patients with malignant melanoma]. Hautarzt. 1984 Feb;35(2):78-83. German. PMID: 6706581; UI: 84161176.
The main side-effects of BCG vaccination by scarification in 511 patients with malignant melanoma since 1974 have been fatigue and exhaustion, swelling of the lymph-nodes, influenza-like symptoms, nausea and dizziness. Only in 8 patients were the side-effects more severe, requiring the cessation of treatment in some of them. One patient developed granulomatous hepatitis, another experienced a reactivation of pulmonary tuberculosis. Allergic reactions occurred in two patients. A further patient developed recurrent erysipelas in the draining areas of the scarification. In two patients we observed continuous severe joint troubles, which were not due to metastatic disease. The eighth patient developed keloids at the vaccination sites on the upper arms. One third of the patients had no side-effects. Altogether vaccinations were tolerated well by most of the patients. Nearly all of them were able to work normally. [See Related Articles]
Villar A, Aguero Balbin R, Bustamante Ruiz A, Jimenez Gomez A.
[Miliary tuberculosis secondary to intravesical instillation of Calmette-Guerin bacilli] Med Clin (Barc). 1992 Jun 20;99(4):158. Spanish. No abstract available. PMID:
1635417 [PubMed - indexed for MEDLINE]
Blancher G, et al. [See Related Articles] [Cervical adenitis due to BCG. Problem of vaccination by oral route]. Bull Mem Soc Med Hop Paris. 1968;119(13):1003-8. French. No abstract available.PMID: 5729342; UI: 69207644.
Chevrel G, Zech C, Miossec P. Severe uveitis followed by reactive arthritis after bacillus Calmette-Guerin therapy. J Rheumatol. 1999 Apr;26(4):1011. No abstract available. PMID: 10229442 [PubMed - indexed for MEDLINE]
Ehrengut W.[BCG-induced inflammation during childhood and in pregnancy. Additionally a contribution to BCG-induced necrotising cerebral arteritis]Klin Padiatr. 1990 Sep-Oct;202(5):303-7. German.PMID: 2214588 [PubMed - indexed for MEDLINE]
Freundlich E, et al. [See Related Articles] Tuberculoid granulomata in the liver after BCG vaccination. Isr J Med Sci. 1969 Jan-Feb;5(1):108-13. No abstract available.PMID: 5796274; UI: 69240421.
DR. Miliary tuberculosis following intravesical BCG treatment. Br J Radiol. 1997 Apr;70(832):429. No abstract available. PMID: 9166085 [PubMed -
indexed for MEDLINE]
Foster DR. Miliary tuberculosis: a complication of intravesical BCG treatment. Australas Radiol. 1998 May;42(2):167-8. No abstract available. PMID: 9599839 [PubMed - indexed for MEDLINE]
Helwig H. [Adverse effects from BCG vaccinations]. Dtsch Med Wochenschr. 1977 May 20;102(20):774. German. No abstract available.PMID: 862528; UI: 77184669
Hennessen W; J Biol Stand, 1977. Observations on a BCG vaccine causing adverse reactions in newborns.
Matyszak MK, Perry VH, "Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-Guerin." Neuroscience 1995 Feb;64(4):967-977.
RW. [On tuberculoses caused by BCG] Prax
Pneumol. 1968 Jun;22(6):379-84. German. No abstract available.PMID: 5697911 [PubMed -
indexed for MEDLINE]
Missioux D, Hermabessiere J, Sauvezie B. Arthritis and iritis after bacillus Calmette-Guerin therapy. J Rheumatol. 1995 Oct;22(10):2010. No abstract available. PMID: 8992017 [PubMed - indexed for MEDLINE]
MN, et al. An unusual complication following BCG vaccination.
Indian Pediatr. 1981 Feb;18(2):140-1. No abstract available.PMID: 7263010; UI: 81262939.[See
Raj B, et al. [See Related Articles] BCG lupus. Indian J Chest Dis Allied Sci. 1986 Apr-Jun;28(2):84-7. No abstract available.PMID: 3596660; UI: 87248909.
Ramirez O, et al. [Lupoid syndrome in "BCG-itis." Report of a case]. Med Cutan Ibero Lat Am. 1986;14(2):87-9. Spanish. PMID: 3528713; UI: 86309722.[See Related Articles]
Rodrigues A, et al. [Lupus vulgaris after BCG vaccination. A clinical case]. Med Cutan Ibero Lat Am. 1990;18(4):224-6. Portugese. PMID: 2077307; UI: 91171665.[See Related Articles]